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Invitrogen
HuR Monoclonal Antibody (3A2)
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FIGURE: 1 / 13
HuR Antibody (39-0600) in ICC/IF
Immunofluorescence analysis of HuR was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with HuR (3A2) Mouse Monoclonal Antibody (Product # 39-0600) at 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A28... View More
Product Details
39-0600
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3A2
Immunogen
Recombinant human HuR protein
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.2-7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV-like protein 1; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; Hu-antigen R; Human antigen R; HuR; unnamed protein product
Gene Aliases: ELAV1; ELAVL1; Hua; HUR; MelG
UniProt ID: (Human) Q15717
Entrez Gene ID: (Human) 1994
lncRNA-mediated post-transcriptional gene silencing
protein import into nucleus
cell proliferation
response to glucose
positive regulation of autophagy
posttranscriptional gene silencing
positive regulation of superoxide anion generation
regulation of mRNA stability
positive regulation of translation
positive regulation of autophagosome size
mRNA stabilization
protein homooligomerization
negative regulation of gene silencing by miRNA
mRNA destabilization
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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