NOTCH1 Monoclonal Antibody (mN1A)

chromatin binding transcription coactivator activity enzyme inhibitor activity transmembrane signaling receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding signaling receptor activity identical protein binding transcription regulator activator activity extracellular matrix glycoprotein

negative regulation of transcription from RNA polymerase II promoter luteolysis epithelial to mesenchymal transition heart looping positive regulation of neuroblast proliferation outflow tract morphogenesis endocardium development endocardium morphogenesis atrioventricular node development coronary vein morphogenesis aortic valve morphogenesis atrioventricular valve morphogenesis coronary sinus valve morphogenesis pulmonary valve morphogenesis mitral valve formation epithelial to mesenchymal transition involved in endocardial cushion formation endocardial cushion morphogenesis cardiac chamber formation cardiac ventricle morphogenesis cardiac atrium morphogenesis cardiac right atrium morphogenesis cardiac left ventricle morphogenesis ventricular trabecula myocardium morphogenesis growth involved in heart morphogenesis regulation of cardioblast proliferation cell migration involved in endocardial cushion formation negative regulation of extracellular matrix constituent secretion pericardium morphogenesis regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter protein import into nucleus immune response Notch signaling pathway positive regulation of transcription of Notch receptor target spermatogenesis determination of left/right symmetry axon guidance heart development positive regulation of cell proliferation negative regulation of cell proliferation gene expression negative regulation of cardiac muscle hypertrophy positive regulation of gene expression negative regulation of gene expression negative regulation of cardiac muscle cell apoptotic process positive regulation of epithelial to mesenchymal transition negative regulation of cell-substrate adhesion negative regulation of myotube differentiation mesenchymal cell development cell differentiation in spinal cord cell differentiation protein catabolic process negative regulation of ossification regulation of cell migration positive regulation of cell migration positive regulation of BMP signaling pathway negative regulation of BMP signaling pathway organ regeneration response to muramyl dipeptide response to lipopolysaccharide negative regulation of collagen biosynthetic process tube formation cellular response to vascular endothelial growth factor stimulus regulation of cell proliferation tissue regeneration negative regulation of catalytic activity positive regulation of viral genome replication positive regulation of endothelial cell differentiation negative regulation of myoblast differentiation negative regulation of neuron differentiation negative regulation of osteoblast differentiation positive regulation of glial cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of JAK-STAT cascade positive regulation of Ras protein signal transduction astrocyte differentiation oligodendrocyte differentiation positive regulation of astrocyte differentiation negative regulation of oligodendrocyte differentiation homeostasis of number of cells within a tissue negative regulation of neurogenesis regulation of developmental process positive regulation of smooth muscle cell differentiation cardiac muscle tissue morphogenesis cardiac muscle cell proliferation positive regulation of cardiac muscle cell proliferation negative regulation of glial cell proliferation cilium morphogenesis cardiac epithelial to mesenchymal transition negative regulation of cell adhesion molecule production cardiac muscle cell myoblast differentiation cardiac septum morphogenesis ventricular septum morphogenesis arterial endothelial cell differentiation venous endothelial cell differentiation cardiac vascular smooth muscle cell development endocardial cell differentiation vasculogenesis involved in coronary vascular morphogenesis coronary artery morphogenesis regulation of cell adhesion involved in heart morphogenesis heart trabecula morphogenesis positive regulation of cardiac epithelial to mesenchymal transition negative regulation of biomineral tissue development positive regulation of ERK1 and ERK2 cascade left/right axis specification cellular response to tumor cell cellular response to follicle-stimulating hormone stimulus cellular response to hypoxia distal tubule development collecting duct development glomerular mesangial cell development T-helper 17 type immune response negative regulation of cell migration involved in sprouting angiogenesis neuronal stem cell population maintenance interleukin-17-mediated signaling pathway chemical synaptic transmission, postsynaptic negative regulation of cold-induced thermogenesis regulation of extracellular matrix assembly positive regulation of apoptotic process involved in morphogenesis negative regulation of cell-cell adhesion mediated by cadherin negative regulation of cell proliferation involved in heart morphogenesis negative regulation of stem cell differentiation negative regulation of anoikis negative regulation of pro-B cell differentiation negative regulation of endothelial cell chemotaxis angiogenesis in utero embryonic development cell fate specification liver development morphogenesis of an epithelial sheet sprouting angiogenesis osteoblast fate commitment epithelial cell development inflammatory response to antigenic stimulus endocardial cushion development cardiac right ventricle formation humoral immune response compartment pattern specification axonogenesis foregut morphogenesis endoderm development epidermis development regulation of Notch signaling pathway auditory receptor cell fate commitment glial cell differentiation regulation of gene expression positive regulation of cell development regulation of somitogenesis neural tube development neuron differentiation keratinocyte differentiation lung development embryonic limb morphogenesis positive regulation of epithelial cell differentiation forebrain development hair follicle morphogenesis embryonic hindlimb morphogenesis epithelial cell differentiation involved in kidney development skeletal muscle cell differentiation regulation of apoptotic process positive regulation of apoptotic process negative regulation of programmed cell death cell fate commitment negative regulation of cell differentiation regulation of auditory receptor cell differentiation negative regulation of auditory receptor cell differentiation positive regulation of keratinocyte differentiation positive regulation of Notch signaling pathway negative regulation of calcium ion-dependent exocytosis negative regulation of photoreceptor cell differentiation somatic stem cell division developmental growth reproductive structure development neuron fate commitment branching morphogenesis of an epithelial tube artery morphogenesis venous blood vessel morphogenesis regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation regulation of neurogenesis secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development prostate gland epithelium morphogenesis regulation of epithelial cell proliferation involved in prostate gland development glomerulus vasculature development nephron tubule development negative regulation of canonical Wnt signaling pathway positive regulation of ephrin receptor signaling pathway apoptotic process involved in embryonic digit morphogenesis positive regulation of aorta morphogenesis regulation of cell proliferation involved in heart morphogenesis animal organ development Notch signaling involved in heart development