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Invitrogen
Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody
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FIGURE: 1 / 2
Phospho-MAPKAPK2 (Thr334) Antibody (44-516G) in WB
Peptide Competition and Phosphatase Treatment: Lysates prepared from HeLa cells left untreated (1), treated with anisomycin (2), or TNF-α (3-7) were either left untreated (1-6) or treated with lambda (l) phosphatase (7). Results indicate specificity for Phospho-MAPKAPK2 Thr334 (Product # 44-516G).
Product Details
44-516G
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human MAPKAPK-2 that contains threonine 334. The sequence is conserved in mouse, hamster and rabbit.
Conjugate
Form
Liquid
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Wet or Dry ice (international)
RRID
Target Information
MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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