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Invitrogen
NDUFS3 Monoclonal Antibody (3F9DD2)
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FIGURE: 1 / 4
NDUFS3 Antibody (459130) in WB
Nutrients 2020 -
Figure 5 HAE activated the mitochondrial biogenesis pathway in mice livers and hearts. Con, control; P407, poloxamer 407; P407 + HAE, poloxamer 407 plus HAE at 200 mg/kg/day. ( A ) Protein levels of liver PGC-1alpha and mitochondrial complex subunits I-V (left, western blot image; right, statistical analysis). ( B ) Liver mtDNA copy number. ( C ) Liver ATP level. ( D ) Protein levels of heart PGC-1alpha and... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
459130
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Published species
Horse,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3F9DD2
Immunogen
Whole mitochondria from Human Heart
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
IgG fraction
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Use Isolated mitochondria from Human, Bovine Rat and Mouse hearts; Cultured Human fibroblasts; HeLa cells; Human colon and cerebellum tissues as positive control.
Target Information
This gene encodes one of the iron-sulfur protein components of mitochondrial NADH:ubiquinone oxidoreductase. Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CI-30kD; complex I 30kDa subunit; complex I iron sulphur protein subunit; 30 kDa subunit; complex I-30kD; NADH dehydrogenase (ubiquinone) Fe-S protein 3; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit; unnamed protein product
Gene Aliases: 0610010M09Rik; CI-30; CI-30kD; MC1DN8
UniProt ID: (Bovine) P23709, (Human) O75489, (Mouse) Q9DCT2
Entrez Gene ID: (Bovine) 287327, (Human) 4722, (Rat) 295923, (Mouse) 68349
negative regulation of cell growth
oxidation-reduction process
reactive oxygen species metabolic process
negative regulation of intrinsic apoptotic signaling pathway
mitochondrial electron transport, NADH to ubiquinone
aerobic respiration
substantia nigra development
mitochondrial respiratory chain complex I assembly
mitochondrial ATP synthesis coupled proton transport
hydrogen ion transmembrane transport
biological_process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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