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Proteintech
VCP Recombinant Rabbit Monoclonal Antibody (3G23)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
82463-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Mammalian cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
3G23
Immunogen
Recombinant protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: GMTPSKGVLF YGPPGCGKTL LAKAIANECQ ANFISIKGPE LLTMWFGESE ANVREIFDKA RQAAPCVLFF DELDSIAKAR GGNIGDGGGA ADRVINQILT EMDGMSTKKN VFIIGATNRP DIIDPAILRP GRLDQLIYIP LPDEKSRVAI LKANLRKSPV AKDVDLEFLA KMTNGFSGAD LTEICQRACK LAIRESIESE IRRERERQTN PSAMEVEEDD PVPEIRRDHF EEAMRFARRS VSDNDIRKYE MFAQTLQQSR GFGSFRFPSG NQGGAGPSQG SGGGTGGSVY TEDNDDDLYG
Target Information
The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 15S Mg(2+)-ATPase p97 subunit; AAA ATPase p97; homolog of yeast cdc48; Inv protein; or HEL-S-70; p97 atpase; TER ATPase; unnamed protein product
Gene Aliases: 3110001E05; CDC48; FTDALS6; p97; p97/VCP; TERA
UniProt ID: (Human) P55072, (Mouse) Q01853, (Rat) P46462
Entrez Gene ID: (Human) 7415, (Mouse) 269523, (Rat) 116643
RNA binding
protein binding
ATP binding
hydrolase activity
ATPase activity
protein phosphatase binding
protein domain specific binding
polyubiquitin binding
ubiquitin protein ligase binding
deubiquitinase activator activity
K48-linked polyubiquitin binding
MHC class I protein binding
identical protein binding
ADP binding
ubiquitin-like protein ligase binding
macromolecular complex binding
ubiquitin-dependent protein binding
BAT3 complex binding
ubiquitin-specific protease binding
mitophagy
DNA repair
double-strand break repair
ubiquitin-dependent protein catabolic process
ER to Golgi vesicle-mediated transport
autophagy
cellular response to DNA damage stimulus
proteasomal protein catabolic process
positive regulation of mitochondrial membrane potential
macroautophagy
protein ubiquitination
peptidyl-lysine trimethylation
viral genome replication
NAD metabolic process
translesion synthesis
endoplasmic reticulum unfolded protein response
retrograde protein transport, ER to cytosol
positive regulation of protein complex assembly
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
endosome to lysosome transport via multivesicular body sorting pathway
cellular response to heat
negative regulation of hippo signaling
stress granule disassembly
interstrand cross-link repair
ERAD pathway
regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein unfolding
establishment of protein localization
positive regulation of protein catabolic process
negative regulation of smoothened signaling pathway
ATP metabolic process
regulation of synapse organization
mitotic spindle disassembly
endoplasmic reticulum stress-induced pre-emptive quality control
cellular response to misfolded protein
rescue of stalled ribosome
flavin adenine dinucleotide catabolic process
positive regulation of canonical Wnt signaling pathway
autophagosome maturation
protein-DNA covalent cross-linking repair
negative regulation of protein localization to chromatin
cytoplasm protein quality control
positive regulation of NIK/NF-kappaB signaling
positive regulation of protein K63-linked deubiquitination
regulation of aerobic respiration
cellular response to arsenite ion
positive regulation of oxidative phosphorylation
regulation of protein localization to chromatin
ribosome-associated ubiquitin-dependent protein catabolic process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of ATP biosynthetic process
I-kappaB kinase/NF-kappaB signaling
aggresome assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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