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Active Motif
H3ac pan-acetyl (K9,K14,K18,K23,K27) Recombinant Rabbit Monoclonal Antibody, AbFlex®
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FIGURE: 1 / 1
H3ac pan-acetyl (K9,K14,K18,K23,K27) Antibody (91419ACTMOTIF) in WB
AbFlexHistone H3ac (pan-acetyl) antibody (rAb) tested by Western blot. HeLa nuclear extract (20 μg per lane) was probed with AbFlexHistone H3ac (pan-acetyl) antibody (0.5 μg/mL). Lane 1: HeLa cells no treatment Lane 2: HeLa cells treated with sodium butyrate.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
91419ACTMOTIF
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
This Histone H3 acetyl antibody was raised against an acetylated Histone H3 peptide.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
32mM sodium acetate/140mM HEPES, pH 7.5, with 30% glycerol, 70mM NaCl
Contains
0.035% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Predicted to react with a wide range of species.
AbFlex® antibodies are recombinant antibodies (rAbs) that have been generated using defined DNA sequences to produce highly specific, reproducible antibodies. Each AbFlex antibody contains a 6xHis Tag, a Biotinylation Tag for enzymatic biotin conjugation using the biotin ligase, BirA, and a sortase recognition motif (LPXTG) to attach a variety of labels directly to the antibody including fluorophores, enzymatic substrates (HRP, AP), peptides, drugs as well as solid supports. | AbFlex® Histone H3ac (pan-acetyl) antibody was expressed as full-length IgG with mouse immunoglobulin heavy and light chains (IgG2a isotype) in mammalian 293 cells
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetyl H3; Acetyl Histone 3; Acetyl Histone H3; H3; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member M; H3 histone, family 2; HIST1H3A; HIST1H3F; histone 1, H3a; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; Histone 3; histone cluster 1 H3 family member a; histone cluster 1 H3 family member f; histone cluster 1 H3 family member h; histone cluster 1, H3a; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2 H3 family member a; histone cluster 2 H3 family member c; histone cluster 2, H3a; histone cluster 2, H3c; Histone H3; histone H3/a; histone H3/i; histone H3/k; histone H3/m; histone H3/o; pan-acetyl H3K9, H3K14, H3K18, H3K23, H3K27; unnamed protein product
Gene Aliases: H3; H3.2; H3/A; H3/i; H3/k; H3/M; H3/n; H3/o; H3F1K; H3F2; H3FA; H3FI; H3FK; H3FM; H3FN; HIST1H3A; HIST1H3F; HIST1H3H; HIST2H3A; HIST2H3C
UniProt ID: (Human) P68431, (Human) Q71DI3
Entrez Gene ID: (Human) 8350, (Human) 8357, (Human) 126961, (Human) 333932, (Human) 8968
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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