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L-Serine, 99%
L-Serine, 99%
L-Serine, 99%
Thermo Scientific Chemicals

L-Serine, 99%

CAS: 56-45-1 | C3H7NO3 | 105.093 g/mol
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Catalog number A11179.36
also known as A11179-36
Price (USD)
337.65
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Ends: 30-Jun-2026
397.00
Save 59.35 (15%)
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Quantity:
500 g
Request bulk or custom format
Price (USD)
337.65
Special offer
Online exclusive
Ends: 30-Jun-2026
397.00
Save 59.35 (15%)
Each
Chemical Identifiers
CAS56-45-1
IUPAC Name2-amino-3-hydroxypropanoic acid
Molecular FormulaC3H7NO3
InChI KeyMTCFGRXMJLQNBG-UHFFFAOYNA-N
SMILESNC(CO)C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to pale cream
FormCrystals or powder or crystalline powder or needles
Assay (Non-aqueous acid-base Titration)≥98.5 to ≤101.5%
Identification (FTIR)Conforms
Optical Rotation+12.5° to +14.0° (c=5, 5N HCl)
L-serine is used as a dietary supplement to improve health under certain conditions of malnutrition or physical stress, as a cosmetic incredient, as ingredients for cell culture media. It is used as a precursor to several amino acids, including glycine, cysteine and other metabolites such as sphingolipids and folate. It is used in bio-synthesis of purines and pyrimidines. It plays a vital role in catalytic function of enzymes. Further, L-serine and its metabolic products are essential for cell proliferation and specific functions of the central nervous system. .

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-serine is used as a dietary supplement to improve health under certain conditions of malnutrition or physical stress, as a cosmetic incredient, as ingredients for cell culture media. It is used as a precursor to several amino acids, including glycine, cysteine and other metabolites such as sphingolipids and folate. It is used in bio-synthesis of purines and pyrimidines. It plays a vital role in catalytic function of enzymes. Further, L-serine and its metabolic products are essential for cell proliferation and specific functions of the central nervous system. .

Solubility
Soluble in water. Insoluble in ethanol, ether and benzene.

Notes
Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Has been used in a synthesis of D-amino acids. The configuration is inverted by conversion of the carboxyl group to the new alkyl chain by reaction with an organolithium reagent to give the ketone, which is deoxygenated by Raney nickel desulfurization of the thioketal, the hydroxymethyl group becoming the new carboxyl group by oxidation with oxygen over a Pt catalyst: J. Am. Chem. Soc., 106, 1095 (1984):
  2. Sim, W. C.; Yin, H. Q.; Choi, H. S.; Choi, Y. J.; Kwak, H. C.; Kim, S. K.; Lee, B. H. l-Serine Supplementation Attenuates Alcoholic Fatty Liver by Enhancing Homocysteine Metabolism in Mice and Rats. J. Nutr. 2015, 145 (2), 260-267.
  3. Zafarani-Moattar, M. T.; Asadzadeh, B. Effect of 1-carboxymethyl-3-methylimidazolium chloride,[HOOCMMIM][Cl], ionic liquid on volumetric, acoustic and transport behavior of aqueous solutions of l-serine and l-threonine at T= 298.15 K. J. Mol. Liq. 2015, 202, 79-85.