D-(+)-Trehalose dihydrate, 99%
D-(+)-Trehalose dihydrate, 99%
D-(+)-Trehalose dihydrate, 99%
D-(+)-Trehalose dihydrate, 99%
Thermo Scientific Chemicals

D-(+)-Trehalose dihydrate, 99%

CAS: 6138-23-4 | C12H22O11 | 342.30 g/mol
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5 g
25 g
100 g
Catalog number A19434.06
also known as A19434-06
Price (USD)
34.30
Each
Quantity:
5 g
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Price (USD)
34.30
Each
Chemical Identifiers
CAS6138-23-4
IUPAC Name(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-3,4,5-triol dihydrate
Molecular FormulaC12H26O13
InChI KeyDPVHGFAJLZWDOC-DJCWUSJTNA-N
SMILESO.O.OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
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SpecificationsSpecification SheetSpecification Sheet
Assay from Supplier's CofA≥98.5%
Water Content (Karl Fischer Titration)8.65-10.80% (1.8-2.3 waters)
Identification (FTIR)Conforms
Optical Rotation+178 ± 4? (c=2 in water)
FormCrystalline powder
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D-(+)-Trehalose dihydrate is used as a food additive in many processed foods and pharmaceutical excipients. It is widely used as a direct replacement of conventional sweeteners and protects the cells from various environmental stresses. It finds application in the treatment of Huntington's disease and Parkinson's disease.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water and hot alcohol.

Notes
Store in cool place. Hygroscopic. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Schultz, I.; Vollmers, F.; Luhmann, T.; Rybak, J. C.; Wittmann, R.; Stank, K.; Steckel, H.; Kardziev, B.; Schmidt, M.; Hogger, P.; Meinel, L. Pulmonary Insulin-like Growth Factor I Delivery from Trehalose and Silk-Fibroin Microparticles. ACS Biomater. Sci. Eng. 2015, 1 (2), 119-129.
  2. Amaro, M. I.; Tajber, L.; Corrigan, O. I.; Healy, A. M. Co-Spray Dried Carbohydrate Microparticles: Crystallisation Delay/Inhibition and Improved Aerosolization Characteristics Through the Incorporation of Hydroxypropyl-beta-cyclodextrin with Amorphous Raffinose or Trehalose. Pharm. Res. 2015, 32 (1), 180-195.