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Bethyl Laboratories
EPB41L2/4.1G Polyclonal Antibody
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FIGURE: 1 / 1
EPB41L2/4.1G Antibody (A301-424A-T) in WB
Detection of human EPB41L2/4.1G by western blot and immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-EPB41L2/4.1G antibody (Product # A301-424A) used for WB at 0.04 µg/mL (A) and 0.1 µg/mL (B) and used for IP at 3 µg/mg lysate. EPB41L2/4.1G was also immunoprecipitated by rabbit anti-EPB41L2/4.1G antibody A301-425A, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 seconds (A and B).
Product Details
A301-424A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 100 and 150 of human erythrocyte membrane protein band 4.1-like 2 (Generally expressed protein 4.1).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4.1N have been reported to detect multiple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4.1B have been reported to detect two forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4.1G; Band 4.1-like protein 2; DKFZp781D1972; DKFZp781H1755; erythrocyte membrane protein band 4.1 like-protein 2; Erythrocyte membrane protein band 4.1-like 2; Generally expressed protein 4.1; OTTHUMP00000040262; RP3-324N14.1; similar to erythroid membrane skeletal protein 4.1; unnamed protein product
Gene Aliases: 4.1-G; 4.1G; EPB41L2
UniProt ID: (Human) O43491
Entrez Gene ID: (Human) 2037
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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