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Bethyl Laboratories
STXBP1/MUNC18-1 Polyclonal Antibody
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FIGURE: 1 / 1
STXBP1/MUNC18-1 Antibody (A305-264A-T) in IP
Detection of human STXBP1 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-STXBP1 antibody (Product # A305-264A) (lot 1) used for IP at 6 µg per reaction. STXBP1 was also immunoprecipitated by rabbit anti-STXBP1 antibody A305-263A. For blotting immuno... View More
Product Details
A305-264A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 544 to 594 of Human Syntaxin-binding protein 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Bovine and Orangutan
Target Information
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EIEE4; FLJ37475; hUNC18; MGC146482; munc-18c; MUNC18-1; N-Sec1; neuronal SEC1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; rop; RP11-56D16.3; Syntaxin-binding protein 1; Unc-18A; Unc18-1; unnamed protein product
Gene Aliases: DEE4; MUNC18-1; N-Sec1; NSEC1; P67; RBSEC1; STXBP1; unc-18A; UNC18; unc18-1; UNC18A
UniProt ID: (Human) P61764
Entrez Gene ID: (Human) 6812
platelet degranulation
developmental process involved in reproduction
intracellular protein transport
exocytosis
vesicle docking involved in exocytosis
neurotransmitter secretion
neuromuscular synaptic transmission
axon target recognition
regulation of synaptic vesicle priming
protein transport
synaptic vesicle priming
synaptic vesicle maturation
vesicle-mediated transport
negative regulation of protein complex assembly
regulation of vesicle fusion
regulation of synaptic vesicle fusion to presynaptic membrane
negative regulation of synaptic transmission, GABAergic
response to estradiol
SNARE complex assembly
regulation of SNARE complex assembly
positive regulation of mast cell degranulation
negative regulation of neuron apoptotic process
regulated exocytosis
positive regulation of exocytosis
positive regulation of calcium ion-dependent exocytosis
protein stabilization
neuron apoptotic process
establishment of localization in cell
long term synaptic depression
platelet aggregation
cellular response to interferon-gamma
protein localization to plasma membrane
presynaptic dense core vesicle exocytosis
positive regulation of vesicle docking
positive regulation of glutamate secretion, neurotransmission
regulation of regulated secretory pathway
regulation of acrosomal vesicle exocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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