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Invitrogen
FCN1 Monoclonal Antibody (5)
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FIGURE: 1 / 3
FCN1 Antibody (ABS 036-05-02) in IHC
Journal of leukocyte biology 2011 -
8 Immunohistochemical staining for M-ficolin. Tissue and cellular distribution of M-ficolin examined with anti-M-ficolin mAb 036-05. (A) Liver (original magnification, x400). Granulocytes and monocytes in blood vessels are stained. Kupffer cells and hepatocytes are not stained. (B) Liver stained with control primary antibody (x400). (C) Lung (original magnification, x400). Strong staining of monocytes/granu... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
ABS 036-05-02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
5
Immunogen
Purified recombinant protein corresponding to residues 95-314 of human M-Ficolin, expressed in prokaryote.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.06 mg/mL
Amount
424 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
ABS 036-05-02 detects M-Ficolin from human samples.
In ELISA application, this antibody reacts with recombinant M-Ficolin coated directly into the microtiter well.
The ABS 036-05-02 immunogen is purified recombinant protein corresponding to residues 95-314 of human M-Ficolin, expressed in prokaryote.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ficolin (collagen/fibrinogen domain-containing) 1; ficolin-A; ficolin-alpha; M-ficolin; unnamed protein product
Gene Aliases: FCNM
UniProt ID: (Human) O00602
Entrez Gene ID: (Human) 2219
complement activation, lectin pathway
cell surface pattern recognition receptor signaling pathway
proteolysis
G-protein coupled receptor signaling pathway
positive regulation of interleukin-8 production
protein localization to cell surface
recognition of apoptotic cell
negative regulation of viral entry into host cell
positive regulation of opsonization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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