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Invitrogen
NGAL Monoclonal Antibody (14)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
ABS 062-14-02
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
14
Immunogen
Human recombinant NGAL coupled to carrier and adsorbed to aluminium hydroxide gel.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.95 mg/mL
Amount
380 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reactivity: ABS 062-14-02 binds human NGAL coated onto a solid phase. ABS 062-14-02 can be used as a detection antibody in a sandwich ELISA with capture antibodies HYB 211-01-02, ABS 038-04-02, ABS 038-14-02, ABS 038-15-02, ABS 038-23-02, ABS 038-26-02 and ABS 062-33-02. When ABS 062-14-02 is used as a biotinylated detection antibody with capture antibody ABS 062-33-02, the assay is specific for the NGAL monomer, cross-reacting less than 1% with NGAL homodimer.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 25 kDa alpha-2-microglobulin-related subunit of MMP-9; HGNC:6526; LCN2; Lipocalin2; migration-stimulating factor inhibitor; neutrophil lipocalin; oncogene 24p3; OTTHUMP00000022240; RP23-161B9.11; siderocalin LCN2; unnamed protein product; uterocalin
Gene Aliases: 24p3; MSFI; NGAL; p25
UniProt ID: (Human) P80188
Entrez Gene ID: (Human) 3934
acute-phase response
response to oxidative stress
short-term memory
long-term memory
response to xenobiotic stimulus
response to bacterium
response to herbicide
response to toxic substance
response to blue light
response to fructose
response to iron(II) ion
response to mycotoxin
positive regulation of endothelial cell migration
positive regulation of gene expression
siderophore transport
positive regulation of cell projection organization
response to nutrient levels
cellular response to nutrient levels
response to lipopolysaccharide
cellular response to increased oxygen levels
defense response to bacterium
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
innate immune response
cellular response to hydrogen peroxide
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to interleukin-6
cellular response to tumor necrosis factor
cellular response to hypoxia
cellular response to X-ray
positive regulation of hippocampal neuron apoptotic process
negative regulation of hippocampal neuron apoptotic process
positive regulation of cold-induced thermogenesis
positive regulation of reactive oxygen species biosynthetic process
response to kainic acid
positive regulation of iron ion import across plasma membrane
cellular response to beta-amyloid
positive regulation of endothelial tube morphogenesis
cellular response to nerve growth factor stimulus
positive regulation of reactive oxygen species metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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