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Invitrogen
Caspase 1 Polyclonal Antibody
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FIGURE: 1 / 9
Caspase 1 Antibody (AHZ0082) in WB
Life (Basel, Switzerland) 2021 -
Figure 3 Androgen treatment of PrECs inhibited cytosolic DNA-induced activation of the AIM2 inflammasome. Cultures of human proliferating PrECs were either treated with vehicle (lanes 1 and 2) or with 10 nM DHT (lanes 3 and 4) for 18 h. Cells treated with either vehicle or DHT were further treated with 10 ng/mL TNF-alpha for 3 h to "prime" cells. The primed cells were either treated with LyoVec (lanes 1 and... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
AHZ0082
Applications
Tested Dilution
Publications
Product Specifications
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide (PEHKTSDSTFLVFMSHGIREG) corresponding to amino acids 129-149 of human Caspase-1, coupled to KLH.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Storage conditions
-20°C
Shipping conditions
Dry ice
RRID
Target Information
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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