Biotin Azide (PEG4 carboxamide-6-Azidohexanyl Biotin)

Citations & References (12)

Invitrogen™

Biotin Azide (PEG4 carboxamide-6-Azidohexanyl Biotin)

ハプテン、ビオチンアジドは、銅触媒クリック反応を介して末端アルキルに反応します。その後、ビオチンはストレプトアビジン、アビジン、またはNeutrAvidin®ビオチン結合タンパク質で検出できます。詳細を見る

製品番号（カタログ番号）	数量
B10184	1 mg

製品番号（カタログ番号） B10184

価格（JPY）

65,100

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ハプテン、ビオチンアジドは、銅触媒クリック反応を介して末端アルキルに反応します。その後、ビオチンはストレプトアビジン、アビジン、またはNeutrAvidin®ビオチン結合タンパク質で検出できます。

研究用にのみ使用できます。診断用には使用いただけません。

化学反応性アルキン

フォーマット固体

標識または色素ビオチン

分子量615.79 Da

製品タイプビオチンアジド

数量1 mg

反応基アジド

反応性部分アミン、アジド

出荷条件室温

溶解性DMSO（ジメチルスルホキシド）

色ビオチン

標識タイプビオチンおよびその他のハプテン

製品ラインMolecular Probes

Unit SizeEach

組成および保存条件

≦-20℃以下の湿気のない場所で保存してください。

引用および参考文献 (12)

引用および参考文献

Abstract

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.

Authors:Kobayashi M, Aida M, Nagaoka H, Begum NA, Kitawaki Y, Nakata M, Stanlie A, Doi T, Kato L, Okazaki IM, Shinkura R, Muramatsu M, Kinoshita K, Honjo T,

Journal:Proc Natl Acad Sci U S A

PubMed ID:20018730

'To initiate class switch recombination (CSR) activation-induced cytidine deaminase (AID) induces staggered nick cleavage in the S region, which lies 5'' to each Ig constant region gene and is rich in palindromic sequences. Topoisomerase 1 (Top1) controls the supercoiling of DNA by nicking, rotating, and religating one strand of DNA. ... More

Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.

Authors:Vila A, Tallman KA, Jacobs AT, Liebler DC, Porter NA, Marnett LJ,

Journal:Chem Res Toxicol

PubMed ID:18232660

'Polyunsaturated fatty acids (PUFA) are primary targets of free radical damage during oxidative stress. Diffusible electrophilic alpha,beta-unsaturated aldehydes, such as 4-hydroxynonenal (HNE), have been shown to modify proteins that mediate cell signaling (e.g., IKK and Keap1) and alter gene expression pathways responsible for inducing antioxidant genes, heat shock proteins, and ... More

A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.

Authors:Luebben SW, Kawabata T, Johnson CS, O'Sullivan MG, Shima N,

Journal:

PubMed ID:24589582

'Accumulating evidence suggests that dormant DNA replication origins play an important role in the recovery of stalled forks. However, their functional interactions with other fork recovery mechanisms have not been tested. We previously reported intrinsic activation of the Fanconi anemia (FA) pathway in a tumor-prone mouse model (Mcm4(chaos3)) with a ... More

Metabolic labeling of sialic acids in living animals with alkynyl sugars.

Authors:Chang PV, Chen X, Smyrniotis C, Xenakis A, Hu T, Bertozzi CR, Wu P,

Journal:Angew Chem Int Ed Engl

PubMed ID:19388017

Sialome sweet sialome: As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living ... More

Regulation of the Skeletal Muscle Ryanodine Receptor/Ca2+-release Channel RyR1 by S-Palmitoylation.

Authors:Chaube R, Hess DT, Wang YJ, Plummer B, Sun QA, Laurita K, Stamler JS,

Journal:

PubMed ID:24509862

The ryanodine receptor/Ca(2+)-release channels (RyRs) of skeletal and cardiac muscle are essential for Ca(2+) release from the sarcoplasmic reticulum that mediates excitation-contraction coupling. It has been shown that RyR activity is regulated by dynamic post-translational modifications of Cys residues, in particular S-nitrosylation and S-oxidation. Here we show that the predominant ... More

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