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Sequence of this protein is as follows: ILKELVTLRA QKSRLLGFHT HADYVLEMNM AKTSQTVATF LDELAQKLKP LGEQERAVIL ELKRAECERR GLPFDGRIRA WDMRYYMNQV EETRYCVDQN
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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