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MYO3A Monoclonal Antibody (5A12)
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Product Details
H00053904-M03A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
5A12
Immunogen
MYO3A (NP_059129, 1400 a.a. approximately 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: HEEINNIKKK DNKDSKATSE REACGLAIFS KQISKLSEEY FILQKKLNEM ILSQQLKSLY LGVSHHKPIN RRVSSQQCLS GVCKGEEPKI L
Target Information
MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily where they are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. MYO3A plays an important role in hearing in humans and mutations in the MYO3A have been shown to cause nonsyndromic progressive hearing loss. MYO3A is highly expressed in retina and cochlea.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: class III myosin; epididymis secretory sperm binding protein; Myosin-IIIa
Gene Aliases: DFNA90; DFNB30; MYO3A
UniProt ID: (Human) Q8NEV4
Entrez Gene ID: (Human) 53904
microfilament motor activity
nucleotide binding
motor activity
actin binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
calmodulin binding
ATP binding
kinase activity
transferase activity
ATPase activity
ADP binding
plus-end directed microfilament motor activity
protein serine kinase activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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