Thermo Scientific Chemicals

L-Homoarginine hydrochloride, 98%, Thermo Scientific Chemicals

Catalog number: H27387.06
5 g, Each
Thermo Scientific Chemicals

L-Homoarginine hydrochloride, 98%, Thermo Scientific Chemicals

Catalog number: H27387.06
5 g, Each
Quantity
Catalog number: H27387.06
also known as H27387-06
Price (USD)
Price: 255.00
Online price: 216.65
Your price:
Quantity
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Chemical Identifiers

CAS
1483-01-8
IUPAC Name
hydrogen 2-amino-6-[(diaminomethylidene)amino]hexanoic acid chloride
Molecular Formula
C7H17ClN4O2
InChI Key
YMKBVNVCKUYUDM-UHFFFAOYNA-N
SMILES
[H+].[Cl-].NC(CCCCN=C(N)N)C(O)=O
Form
Crystals or powder or crystalline powder or granules
Appearance (Color)
White
Assay from Supplier's CofA
≥97.5%
Optical Rotation
18.0 ± 2.0° (C=1 in 1N HCl)

Description

An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.

Solubility
Soluble in water(50 mg/mL).

Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. Refrigerated(2-7°C).
RUO – Research Use Only

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