Thermo Scientific Chemicals

6-Chloropurine riboside, 98%, Thermo Scientific Chemicals

Catalog number: H59634.03
1 g, Each
Thermo Scientific Chemicals

6-Chloropurine riboside, 98%, Thermo Scientific Chemicals

Catalog number: H59634.03
1 g, Each
Quantity
Catalog number: H59634.03
also known as H59634-03
Price (USD)
Price: 118.00
Online price: 100.65
Your price:
Quantity
-

Chemical Identifiers

CAS
5399-87-1
IUPAC Name
2-(6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular Formula
C10H11ClN4O4
InChI Key
XHRJGHCQQPETRH-UHFFFAOYNA-N
SMILES
OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12
Assay (HPLC)
>97.5%

Description

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Solubility
Soluble in water. (10.6 mg/mL)

Notes
Keep away from heat and humidity. Incompatible with strong oxidizing agents.
RUO – Research Use Only

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text