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Invitrogen

PTGER2/PTGER3 Monoclonal Antibody (3F12)

View all (2) PTGER2/PTGER3 antibodies

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Product Details

MA1-12677

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

3F12

Immunogen

Recombinant human EP2 and EP3 receptor protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.11 mg/mL

Amount

100 µg

Purification

Protein A/G

Storage buffer

PBS

Contains

0.08% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2269160

Product Specific Information

A suggested positive control for this product is porcine brain lysate.

Target Information

This polyclonal antibody was raised in Rabbit against PTGER3 / EP3. This antibody has been conjugated with Unconjugated. This antibody is useful for testing in the following assays: IHC-P. The specificity of this antibody has been described as follows: Human PTGER3 / EP3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EP2 receptor; EP3 prostanoid receptor EP3-III isoform; G-protein coupled receptor; G-protein coupled receptor; PTGER3; PGE receptor EP2 subtype; PGE receptor EP3 subtype; PGE receptor, EP2 subtype; PGE receptor, EP3 subtype; PGE2 receptor EP2 subtype; PGE2 receptor EP3 subtype; PGE2 receptor splice variant; isoform EP3-I; prostaglandin E receptor 2 (EP2 subtype); prostaglandin E receptor 2 (subtype EP2); prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E receptor 3 (subtype EP3); prostaglandin E receptor EP2 subtype; prostaglandin E receptor EP3 subtype; prostaglandin E receptor subtype EP2; prostaglandin E2 receptor EP2 subtype-like; prostaglandin E2 receptor type 2; prostaglandin receptor (PGE-2); prostanoid EP2 receptor; prostanoid EP3 receptor; unnamed protein product

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Gene Aliases: COX-2; EP2; EP3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3-VI; EP3e; EP3R; lnc003875; PGE2-R; Pgerep3; Ptger-ep2; Ptgerep2; Ptgerep3; Rep3; rEP3a; rEP3b

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UniProt ID: (Human) P43116, (Human) P43115, (Mouse) Q62053, (Rat) Q62928, (Rat) P34980

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Entrez Gene ID: (Human) 5732, (Human) 5733, (Mouse) 19217, (Rat) 81752, (Mouse) 19218, (Rat) 24929

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Function(s)
G-protein coupled receptor activity prostaglandin E receptor activity prostaglandin receptor activity protein binding prostanoid receptor activity
Process(es)
cAMP biosynthetic process inflammatory response G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration negative regulation of cell proliferation response to nematode regulation of circadian sleep/wake cycle, wakefulness positive regulation of bone mineralization response to lipopolysaccharide response to progesterone negative regulation of interleukin-1 alpha production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of interleukin-10 production positive regulation of interleukin-6 production response to lipid positive regulation of glial cell apoptotic process positive regulation of ion transmembrane transport regulation of cell proliferation vasodilation regulation of circadian sleep/wake cycle, REM sleep positive regulation of neuron apoptotic process positive regulation of osteoblast differentiation positive regulation of ossification negative regulation of smooth muscle contraction positive regulation of circadian sleep/wake cycle, non-REM sleep cAMP metabolic process micturition maternal process involved in female pregnancy negative regulation of mucus secretion cellular response to prostaglandin E stimulus regulation of nitric oxide metabolic process positive regulation of hippocampal neuron apoptotic process negative regulation of hippocampal neuron apoptotic process surfactant secretion positive regulation of p38MAPK cascade negative regulation of compound eye retinal cell apoptotic process positive regulation of glutamate secretion, neurotransmission negative regulation of microglial cell migration positive regulation of gastric mucosal blood circulation negative regulation of endothelin secretion positive regulation of DNA biosynthetic process fever generation positive regulation of protein phosphorylation desensitization of G-protein coupled receptor protein signaling pathway adenylate cyclase-modulating G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway positive regulation of gene expression negative regulation of norepinephrine secretion regulation of norepinephrine secretion intestine smooth muscle contraction urinary bladder smooth muscle contraction bicarbonate transport positive regulation of fever generation receptor internalization negative regulation of interleukin-8 production positive regulation of urine volume positive regulation of vasoconstriction negative regulation of insulin secretion smooth muscle contraction involved in micturition negative regulation of gastric acid secretion positive regulation of mucus secretion negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway cAMP/PKA signal transduction negative regulation of potassium ion transmembrane transport positive regulation of pri-miRNA transcription from RNA polymerase II promoter negative regulation of calcium ion transmembrane transport negative regulation of gastrin-induced gastric acid secretion cellular response to forskolin positive regulation of inhibitory G-protein coupled receptor phosphorylation negative regulation of circadian sleep/wake cycle, wakefulness positive regulation of myofibroblast contraction positive regulation of colon smooth muscle contraction negative regulation of small intestine smooth muscle contraction positive regulation of calcitonin secretion positive regulation of substance P secretion prostaglandin receptor internalization positive regulation of neutrophil extravasation negative regulation of forebrain neuron differentiation negative regulation of apoptotic process negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress cell death response to estradiol cellular response to lipopolysaccharide cellular response to interleukin-1 response to salt
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