Search
Invitrogen
RAN Monoclonal Antibody (ARAN1)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 4
RAN Antibody (MA1-20581) in ICC/IF
Immunofluorescence analysis of RAN was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with RAN Monoclonal Antibody (ARAN1) (Product # MA1-20581) at 5 µg/mL in 0.1% BSA, incubated at 4 degree celsius overnight and then with Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32766) at a dilutio... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-20581
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Hamster,
Human,
Mouse,
Rat,
Xenopus
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
ARAN1
Immunogen
Denatured recombinant human Ran.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.3 mg/mL
Amount
115 µg
Purification
purified
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Jurkat.
Target Information
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: androgen receptor-associated protein 24; ARA25; G protein; G protein; RAN/TC4; ARA24; GTP-binding nuclear protein Ran; GTP-binding protein; GTPase Ran; guanosine triphosphatase Ran; member RAS oncogene family; OTTHUMP00000166078; OTTHUMP00000166102; RAN; ran GTP-binding protein; RAN, member RAS oncogene family; RanGTPase; ras-like protein; ras-like protein TC4; ras-related nuclear protein; unnamed protein product
Gene Aliases: ARA24; Gsp1; I79_024397; ran; ran-1; RanTC4; TC4; XELAEV_18007741mg; xran
UniProt ID: (Bovine) Q3T054, (Human) P62826, (Mouse) P62827, (Rat) P62828, (Xenopus) P52301
Entrez Gene ID: (Bovine) 540457, (Human) 5901, (Chinese hamster) 100769066, (Mouse) 19384, (Rat) 84509, (Xenopus) 108716335
magnesium ion binding
GTPase activity
GTP binding
chromatin binding
RNA binding
obsolete small monomeric GTPase activity
nuclear export signal receptor activity
protein binding
GDP binding
cadherin binding
protein heterodimerization activity
pre-miRNA binding
protein domain specific binding
macromolecular complex binding
dynein intermediate chain binding
importin-alpha family protein binding
RISC complex binding
small GTPase
mitotic sister chromatid segregation
protein import into nucleus
protein export from nucleus
actin cytoskeleton organization
cellular protein complex localization
GTP metabolic process
cell division
snRNA import into nucleus
ribosomal subunit export from nucleus
ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
mitotic cell cycle
DNA metabolic process
nucleocytoplasmic transport
mitotic spindle organization
viral process
pre-miRNA export from nucleus
positive regulation of protein import into nucleus
protein localization to nucleolus
glycolytic process
protein localization
protein complex localization
spermatid development
hippocampus development
positive regulation of protein export from nucleus
cellular response to mineralocorticoid stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support