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Invitrogen
Osteocalcin Monoclonal Antibody (OCG4)
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FIGURE: 1 / 2
Osteocalcin Antibody (MA1-20788) in IHC (P)
Immunohistochemistry of bone substitute stained for Osteocalcin using Anti-Osteocalcin Monoclonal Antibody (Product # MA1-20788). Bone substitute (hydroxyapatite and silicon) was implanted subcutaneously into sheep for 12 weeks. After a series of deparaffinization, rehydration, and blocking steps, paraffin-embedded bone sections were stained with MA1-20788 (1:10 diluted in 10% normal goat serum in 1X PBS) f... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-20788
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Chicken,
Goat,
Human,
Sheep,
Pig,
Rabbit
Published species
Pig,
Rabbit
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OCG4
Immunogen
Bovine osteocalcin.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody does not detect rat or mouse Osteocalcin.
Predicted molecular weight: 12kDa.
Target Information
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BGP; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate; BGLAP; Bone Gla protein; bone gla protein BGP; gamma-carbooxyglutamate (gla) protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin; PMF1; RP11-54H19.5; unnamed protein product
Gene Aliases: BGP; GLA; OC; OCN
UniProt ID: (Human) P02818, (Bovine) P02820
Entrez Gene ID: (Human) 632, (Chicken) 396348, (Sheep) 677670, (Bovine) 281646, (Rabbit) 100340503, (Pig) 397530, (Goat) 100861188
skeletal system development
ossification
osteoblast differentiation
positive regulation of neurotransmitter secretion
cell adhesion
signal transduction
brain development
learning or memory
response to xenobiotic stimulus
response to mechanical stimulus
response to gravity
response to zinc ion
response to activity
bone mineralization
regulation of bone mineralization
response to nutrient levels
response to vitamin K
response to insulin
cellular response to insulin stimulus
response to vitamin D
response to testosterone
response to hydroxyisoflavone
cellular response to zinc ion starvation
response to macrophage colony-stimulating factor
glucose homeostasis
response to estrogen
type B pancreatic cell proliferation
regulation of bone resorption
response to ethanol
regulation of osteoclast differentiation
system development
stem cell differentiation
cognition
response to glucocorticoid
bone development
cellular response to vitamin D
cellular response to growth factor stimulus
regulation of cellular response to insulin stimulus
negative regulation of bone development
regulation of testosterone biosynthetic process
biomineral tissue development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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