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Invitrogen
Cdc7 Monoclonal Antibody (SPM171)
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Product Details
MA1-21285
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
SPM171
Immunogen
Recombinant full length protein (Human).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
50 µg
Storage conditions
4°C
Shipping conditions
Wet ice
RRID
Product Specific Information
MA1-21285 detects Cdc7 Kinase in Human samples.
MA1-21285 has been successfully used in Immunohistochemistry (Paraffin), Immunoprecipitation and Western Blot procedures.
MA1-21285 immunogen corresponds to Recombinant full length protein (Human)..
Target Information
CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines. CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase. CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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