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Invitrogen
Sarcomeric alpha Actinin Monoclonal Antibody (EA-53)
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Product Details
MA1-22863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat,
Zebrafish
Published species
Human,
Mouse,
Pig,
Rat,
Zebrafish
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
EA-53
Immunogen
Purified rabbit skeletal alpha-actinin.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
Ascites
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-22863 detects sarcomeric alpha Actinin in bovine, feline, chicken, fish, goat, hamster, lizard, mouse porcine, rabbit, rat, ovine, snake, and Xenopus laevis samples.
Target Information
This antibody is specific for alpha-skeletal muscle actinin and alpha-cardiac actinin. It stains Z lines and dots in stress fibers of myotubes in skeletal and cardiac muscle but not in non-sarcomeric muscle elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actinin 1 smooth muscle; alpha actinin 1a; Alpha-actinin cytoskeletal isoform; Alpha-actinin-1; epididymis secretory sperm binding protein; F-actin cross-linking protein; non-muscle alpha-actinin 1; Non-muscle alpha-actinin-1; unnamed protein product
Gene Aliases: 3110023F10Rik; ACTN1; Actn1a; BDPLT15
UniProt ID: (Human) P12814, (Rat) Q9Z1P2, (Mouse) Q7TPR4
Entrez Gene ID: (Rabbit) 100341378, (Human) 87, (Rat) 81634, (Mouse) 109711, (Zebrafish) 560400
transcription coactivator activity
double-stranded RNA binding
actin binding
integrin binding
calcium ion binding
protein binding
cytoskeletal protein binding
vinculin binding
identical protein binding
protein homodimerization activity
ion channel binding
metal ion binding
actin filament binding
structural constituent of postsynapse
protein domain specific binding
ligand-dependent nuclear receptor transcription coactivator activity
focal adhesion assembly
actin filament bundle assembly
negative regulation of cellular component movement
actin crosslink formation
regulation of nucleic acid-templated transcription
cortical cytoskeleton organization
actin filament organization
actin cytoskeleton organization
platelet activation
platelet formation
platelet morphogenesis
regulation of apoptotic process
positive regulation of transcription, DNA-templated
anatomical structure formation involved in morphogenesis
actin filament network formation
muscle cell development
platelet aggregation
postsynapse organization
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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