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Invitrogen
Sarcomeric alpha Actinin Monoclonal Antibody (EA-53)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-22863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat,
Zebrafish
Published species
Human,
Mouse,
Pig,
Rat,
Zebrafish
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
EA-53
Immunogen
Purified rabbit skeletal alpha-actinin.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
Ascites
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-22863 detects sarcomeric alpha Actinin in bovine, feline, chicken, fish, goat, hamster, lizard, mouse porcine, rabbit, rat, ovine, snake, and Xenopus laevis samples.
Target Information
This antibody is specific for alpha-skeletal muscle actinin and alpha-cardiac actinin. It stains Z lines and dots in stress fibers of myotubes in skeletal and cardiac muscle but not in non-sarcomeric muscle elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actinin 1 smooth muscle; alpha actinin 1a; bs-alpha actinin 1; epididymis secretory sperm binding protein; F-actin cross-linking protein; non-muscle alpha-actinin-1; unnamed protein product
Gene Aliases: 3110023F10Rik; Actn1a; BDPLT15
UniProt ID: (Human) P12814, (Mouse) Q7TPR4, (Rat) Q9Z1P2
Entrez Gene ID: (Rabbit) 100341378, (Human) 87, (Mouse) 109711, (Rat) 81634, (Zebrafish) 560400
transcription coactivator activity
double-stranded RNA binding
integrin binding
calcium ion binding
protein binding
cytoskeletal protein binding
vinculin binding
identical protein binding
protein homodimerization activity
ion channel binding
actin filament binding
structural constituent of postsynapse
cytoskeletal regulatory protein binding
protein domain specific binding
actin binding
actin filament organization
actin cytoskeleton organization
platelet formation
cortical cytoskeleton organization
platelet morphogenesis
positive regulation of transcription, DNA-templated
focal adhesion assembly
actin filament bundle assembly
actin filament network formation
muscle cell development
postsynapse organization
actin crosslink formation
platelet activation
regulation of apoptotic process
anatomical structure formation involved in morphogenesis
platelet aggregation
fibril organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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