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Invitrogen
Hairy Cell Leukemia Monoclonal Antibody (DBA.44)
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Product Details
MA1-26241
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
DBA.44
Immunogen
Deau cell line established from a large cell lymphoma.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
tissue culture supernatant
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Tonsil.
Target Information
Hairy Cell Leukemia (HCL) is a rare form of mature B-cell cancer characterized by the presence of abnormal B-cells known as "hairy cells." These cells have a distinct genetic profile that plays a significant role in the diagnosis and management of the disease. HCL includes variants such as the hairy cell leukemia variant (HCL-V) and splenic diffuse red pulp lymphoma (SDRPL), which are often detected through specific immunophenotyping and genetic analyses. One critical aspect of these analyses involves the use of flow cytometry to detect lambda light chain restriction among B-cells displaying bright CD11c positivity. Advances in genetic profiling using techniques like clonal analysis with consensus primer polymerase chain reaction (PCR) for heavy chain genes have further refined diagnostic precision, distinguishing HCL from its variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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