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Invitrogen
HTLV-2 env 801 Monoclonal Antibody (8.A.033)
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Product Details
MA1-91454
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
8.A.033
Immunogen
Highly purified HTLV-II envelope 801 antigen.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
25 µg
Purification
Protein G
Storage buffer
0.1M tris HCl, pH 7.5
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-91454 detects HTLV2 env 801 from human samples.
Target Information
The HTLV-2 env 801 gene encodes the envelope glycoprotein, which is pivotal for virus entry into host cells. Human T-cell leukemia virus type 2 (HTLV-2) shares many structural features with HTLV-1, with the envelope (Env) protein being a critical component in mediating viral entry via interaction with cell surface receptors. The env gene product is synthesized as a precursor that is cleaved into the surface (SU) and transmembrane (TM) subunits. The SU subunit facilitates receptor binding, while the TM subunit aids in membrane fusion, enabling the virus to enter the host cell. HTLV-2 predominantly targets and transforms CD8+ T-cells, distinct from HTLV-1, which primarily transforms CD4+ T-cells. Understanding the structural and functional nuances of the HTLV-2 envelope protein is crucial as it presents a target for therapeutic interventions aimed at preventing viral entry and subsequent infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HTLV; HTLV-II; HTLV2
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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