Search
Invitrogen
Fibrillarin Monoclonal Antibody (38F3)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 14
Fibrillarin Antibody (MA3-16771) in ICC/IF
Immunofluorescence analysis of Fibrillarin was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Fibrillarin Monoclonal Antibody (38F3) (Product # MA3-16771) at 1:250 dilution in 0.1% BSA, incubated at 4 degr... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA3-16771
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
C. elegans,
Chicken,
Fruit fly,
Horse,
Human,
Mouse,
Plant,
Pig,
Rat,
Yeast
Published species
Human,
Mouse,
Plant,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
38F3
Immunogen
Yeast nuclear preparation (S. cerevisiae).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. not determined
Storage buffer
tissue culture supernatant
Contains
0.035% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: antigen standard for FBL (transient overexpression lysate).
Target Information
Nop1p / Fibrillarin was originally identified as a nucleolar protein of bakers yeast, Saccharomyces cerevisiae (accession P15646). The Nop1p protein is essential for yeast viability and is localized in the nucleoli. The human homologue of Nop1p is fibrillarin (accession P22087) a component of the nucleolar small nuclear ribonucleoprotein (snRNP) particle. The human fibrillarin gene is located on chromosome 19 (19q13. 1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; AT20009p; CG5725-PA; CG5725-PB; CG5725-PC; CG5725-PD; CG5725-PE; CG5725-PF; CG5725-PG; FBL; fbl-PA; fbl-PB; fbl-PC; fbl-PD; fbl-PE; fbl-PF; fbl-PG; fibrillarin; histone-glutamine methyltransferase; LD24618p; LP11571p; nucleolar protein 1; pantothenate kinase; RNA, U3 small nucleolar interacting protein 1; U6 snRNA 2'-O-methyltransferase fibrillarin; unnamed protein product
Gene Aliases: CELE_T01C3.7; CG5725; Dmel\CG5725; Dmel_CG5725; dPANK; dPANK/Fbl; Fbl; FIB; FLRN; LOT3; Nop1; PANK; RNU3IP1; YDL014W
TFIID-class transcription factor binding
RNA binding
protein binding
methyltransferase activity
rRNA methyltransferase activity
protein-glutamine N-methyltransferase activity
ATPase binding
RNA 2'-O-methyltransferase activity
U6 snRNA 2'-O-ribose methyltransferase activity
histone-glutamine methyltransferase activity
transferase activity
pantothenate kinase activity
ATP binding
RNA processing factor
kinase
transferase
metabolite interconversion enzyme
rRNA 2'-O-methylation
box C/D snoRNA 3'-end processing
osteoblast differentiation
chromatin remodeling
rRNA processing
mRNA modification
maturation of SSU-rRNA
rRNA methylation
ribosomal small subunit biogenesis
snoRNA localization
biological_process
snoRNA metabolic process
methylation
ribosome biogenesis
snoRNA processing
histone glutamine methylation
mitotic cell cycle
response to oxidative stress
chromosome segregation
spermatogenesis
imaginal disc-derived wing morphogenesis
coenzyme A biosynthetic process
regulation of cytokinesis
locomotion
locomotor rhythm
oogenesis
meiotic cell cycle
membrane organization
triglyceride homeostasis
cellular response to gamma radiation
nucleologenesis
positive regulation of translation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support