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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Clone 373E1 is specific for the keratan sulfate bearing molecular complex.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 min followed by cooling at room temperature for 20 min. Recommended positive control: papillary thyroid carcinoma.
Papillary carcinoma is by far the most frequent malignant tumor of the thyroid with a threefold prevelance in females. Studies have shown that 100% of malignant thyroid lesions were found to contain the keratan sulfate (KS) bearing molecules, while these were virtually absent from benign tissues and other thyroid tumors, with the exception of 21% of follicular carcinoma cases analyzed.
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