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Invitrogen
p57 Kip2 Monoclonal Antibody (KP39)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-14361
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
KP39
Immunogen
Recombinant human p57Kip2 protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Amount
25 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-14361 targets p57Kip2 in IHC (P) and IP applications and shows reactivity with Human and mouse samples.
The MA5-14361 immunogen is recombinant human p57Kip2 protein.
Target Information
This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beckwith Wiedemann syndrome (WBS); Cyclin dependent kinase inhibitor 1C (CDKN1C); cyclin dependent kinase inhibitor 1C (P57); cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; IMAGE; p57 Kip2; unnamed protein product
Gene Aliases: BWCR; BWS; CDKI; KIP2; p57; p57(kip2); p57Kip2; WBS
UniProt ID: (Human) P49918, (Mouse) P49919
Entrez Gene ID: (Human) 1028, (Mouse) 12577
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of mitotic cell cycle
negative regulation of epithelial cell proliferation
regulation of cell cycle
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
kidney development
placenta development
regulation of exit from mitosis
myeloid cell differentiation
adrenal gland development
multicellular organism growth
neuron maturation
camera-type eye development
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
digestive system development
uterus development
embryonic placenta morphogenesis
genetic imprinting
regulation of lens fiber cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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