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Invitrogen
LPL Monoclonal Antibody (2C5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-15503
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C5
Immunogen
Purified recombinant fragment of LPL expressed in E. Coli.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-15503 targets LPL in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15503 immunogen is purified recombinant fragment of LPL expressed in E. Coli.
MA5-15503 detects LPL which has a predicted molecular weight of approximately 53.1kDa.
Target Information
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha lipase; lipoprotein lipase precursor; LPL; phospholipase A1; unnamed protein product
Gene Aliases: HDLCQ11; LIPD
UniProt ID: (Human) P06858
Entrez Gene ID: (Human) 4023
lipoprotein lipase activity
phospholipase activity
triglyceride lipase activity
receptor binding
calcium ion binding
protein binding
heparin binding
phosphatidylcholine 1-acylhydrolase activity
lipase activity
apolipoprotein binding
protein homodimerization activity
heparan sulfate proteoglycan binding
protein anchor
carboxylic ester hydrolase activity
lipoprotein particle binding
retinoid metabolic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
triglyceride metabolic process
phospholipid metabolic process
response to glucose
positive regulation of macrophage derived foam cell differentiation
positive regulation of lipid storage
positive regulation of cholesterol storage
lipid catabolic process
triglyceride catabolic process
cellular response to nutrient
positive regulation of chemokine production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
chylomicron remodeling
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
very-low-density lipoprotein particle clearance
cholesterol homeostasis
positive regulation of fat cell differentiation
positive regulation of inflammatory response
low-density lipoprotein particle mediated signaling
triglyceride homeostasis
cellular response to fatty acid
positive regulation of adipose tissue development
positive regulation of triglyceride transport
positive regulation of chemokine (C-X-C motif) ligand 2 production
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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