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Invitrogen

HSP90 alpha Monoclonal Antibody (5G5)

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View all (34) HSP90 alpha antibodies

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Product Details

MA5-17091

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000
-

Flow Cytometry (Flow)

1:200-1:400
-

ELISA (ELISA)

1:10,000
-
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

5G5

Immunogen

Purified recombinant fragment of human HSP90AA1 expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538562

Product Specific Information

MA5-17091 targets HSP90AA1 in indirect ELISA, FACS, IHC and WB applications and shows reactivity with Human, Mouse, and Non-human primate samples.

The MA5-17091 immunogen is purified recombinant fragment of human HSP90AA1 expressed in E. Coli.

MA5-17091 detects HSP90AA1 which has a predicted molecular weight of approximately 90kDa.

Target Information

Heat shock proteins (HSP) are proteins that are expressed in response to various biological stress, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, and some kinases. It has been suggested that HSP90 is necessary to maintain structural integrity of at least some steroid receptors to allow for ligand binding during receptor activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; Heat shock protein; heat shock protein 1, alpha; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein family C member 1; heat shock protein, 1; heat shock protein, 86 kDa 1; heat shock protein, 89 kDa; Heat shock protein90; heat-shock protein hsp86; HSP; HSP 86; HSP 90 alpha; HSP86; lipopolysaccharide-associated protein 2; LPS-associated protein 2; renal carcinoma antigen NY-REN-38; TSTA; tumor-specific transplantation 86 kDa antigen; unnamed protein product

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Gene Aliases: 86kDa; 89kDa; EL52; HEL-S-65p; Hsp103; hsp4; HSP86; Hsp86-1; Hsp89; HSP89A; Hsp90; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; LAP-2; LAP2

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UniProt ID: (Human) P07900, (Mouse) P07901

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Entrez Gene ID: (Human) 3320, (Mouse) 15519

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Function(s)
UTP binding CTP binding RNA binding mRNA binding protein binding ATP binding GTP binding ATPase activity sulfonylurea receptor binding protein phosphatase binding MHC class II protein complex binding nitric-oxide synthase regulator activity TPR domain binding ubiquitin protein ligase binding dATP binding AP-3 adaptor complex binding identical protein binding protein homodimerization activity histone deacetylase binding protein binding involved in protein folding ion channel binding tau protein binding GTPase binding Rho GDP-dissociation inhibitor binding DNA polymerase binding scaffold protein binding disordered domain specific binding ATP-dependent protein folding chaperone enzyme-substrate adaptor activity protein tyrosine kinase binding
Process(es)
neuron migration response to dietary excess activation of innate immune response positive regulation of defense response to virus by host skeletal muscle contraction protein folding nitric oxide biosynthetic process response to unfolded protein response to heat response to cold response to xenobiotic stimulus response to salt stress positive regulation of lamellipodium assembly cardiac muscle cell apoptotic process negative regulation of striated muscle cell apoptotic process protein import into mitochondrial matrix regulation of protein ubiquitination positive regulation of protein polymerization response to follicle-stimulating hormone positive regulation of interferon-beta production regulation of protein localization cellular response to heat response to isolation stress cellular response to platelet-derived growth factor stimulus protein refolding response to cocaine positive regulation of protein import into nucleus regulation of apoptotic process response to estrogen positive regulation of nitric oxide biosynthetic process positive regulation of cytotoxic T cell differentiation positive regulation of protein catabolic process positive regulation of cell size response to antibiotic protein stabilization chaperone-mediated protein complex assembly protein maturation positive regulation of cardiac muscle contraction response to caloric restriction cellular response to hydrogen peroxide cellular response to lipopolysaccharide cellular response to mechanical stimulus cellular response to hypoxia cellular response to virus regulation of postsynaptic membrane neurotransmitter receptor levels neurofibrillary tangle assembly telomerase holoenzyme complex assembly mitochondrial transport telomere maintenance via telomerase positive regulation of telomere maintenance via telomerase regulation of protein complex assembly protein unfolding nitric oxide metabolic process chaperone-mediated autophagy
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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