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Invitrogen
RAE1 delta Monoclonal Antibody (186107)
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FIGURE: 1 / 1
RAE1 delta Antibody (MA5-23889) in Flow
Flow cytometry of RAE1 delta in RAW 264.7 mouse monocyte/macrophage cell line. Samples were incubated in RAE1 delta monoclonal antibody (Product # MA5-23889) or isotype control antibody followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-23889
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
186107
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Rae-1delta Leu29-Ser227
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes Rae-1 alpha, beta, gamma, gamma and epsilon.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Rae-1 delta is one of several known murine NKG2D ligands that include RAE-1 molecules, H60 and MULT-1. Expression of NKG2D ligands is low or absent on normal adult tissues. However, stressed or transformed cells express NKG2D ligands which in turn activates NK cells tumoricidal activity through NKG2D. Until now, the expression of NKG2D ligands has been mainly studied with NKG2D tetramers which recognizes all NKG2D ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RAE-1 delta; GPI-anchored membrane glycoprotein; RAE-1-delta; retinoic acid early transcript 1D
Gene Aliases: RAE-1delta
UniProt ID: (Mouse) Q9JI58
Entrez Gene ID: (Mouse) 56554
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
signal transduction
natural killer cell mediated cytotoxicity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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