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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse A33 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
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Protein Aliases: glycoprotein A33 (transmembrane); MGC129986; MGC129987; transmembrane glycoprotein A33; unnamed protein product
Gene Aliases: A33
UniProt ID: (Human) Q99795
Entrez Gene ID: (Human) 10223
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