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Invitrogen
PSMA4 Monoclonal Antibody (OTI2D12)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-25838
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2D12
Immunogen
Full length human recombinant protein of PSMA4 produced in HEK293T cell
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.79 mg/mL
Amount
79 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-3; macropain subunit C9; MGC111191; MGC12467; MGC24813; multicatalytic endopeptidase complex subunit C9; proteasome (prosome, macropain) subunit, alpha type, 4; proteasome component C9; proteasome subunit alpha 4; proteasome subunit alpha-3; proteasome subunit alpha3; proteasome subunit HC9; proteasome subunit L; PSMA 4; unnamed protein product
Gene Aliases: HC9; HsT17706; PSC9
UniProt ID: (Human) P25789
Entrez Gene ID: (Human) 5685
immune system process
DNA repair
ubiquitin-dependent protein catabolic process
apoptotic process
cellular response to DNA damage stimulus
response to oxidative stress
spermatogenesis
proteasomal protein catabolic process
proteasomal ubiquitin-independent protein catabolic process
protein catabolic process
sperm motility
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of tumor necrosis factor production
response to interferon-gamma
proteasome-mediated ubiquitin-dependent protein catabolic process
CD8-positive, alpha-beta T cell differentiation
thymic T cell selection
T-helper 1 cell differentiation
negative regulation of regulatory T cell differentiation
meiotic cell cycle
regulation of proteasomal protein catabolic process
cellular response to type I interferon
T-helper 17 cell differentiation
CD8-positive, alpha-beta T cell homeostasis
regulation of G1/S transition of mitotic cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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