Search
Invitrogen
Cullin 4A Monoclonal Antibody (GT2435)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 4
Cullin 4A Antibody (MA5-27795) in ICC/IF
Cullin 4A Monoclonal Antibody (GT2435) detects Cullin 4a protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Cullin 4a protein stained by Cullin 4A Monoclonal Antibody (GT2435) (Product # MA5-27795) diluted at 1:200. Red: Phalloidin, a cytoskeleton marker, diluted at 1:100. Scale bar = 10 µm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-27795
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
GT2435
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Cullin 4a. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: HeLa
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CUL 4A; CUL-4A; Cul4a protein; MGC36573; MGC64071; OTTHUMP00000018753; ubiquitin E3 ligase; unnamed protein product
UniProt ID: (Human) Q13619
Entrez Gene ID: (Human) 8451
G1/S transition of mitotic cell cycle
in utero embryonic development
nucleotide-excision repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
spermatogenesis
cell proliferation
regulation of autophagy
protein ubiquitination
regulation of DNA-dependent DNA replication initiation
replication fork processing
developmental process
regulation of natural killer cell activation
cellular response to UV
regulation of gene expression, epigenetic
T cell activation
regulation of cell proliferation
ribosome biogenesis
regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
regulation of embryonic development
regulation of protein metabolic process
regulation of gene silencing by miRNA
regulation of cellular response to stress
intrinsic apoptotic signaling pathway
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
regulation of cell cycle phase transition
regulation of mitotic cytokinesis
negative regulation of adipose tissue development
regulation of stem cell population maintenance
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support