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Invitrogen
ENPP7 Monoclonal Antibody (10)
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FIGURE: 1 / 1
ENPP7 Antibody (MA5-29243) in ICC/IF
Immunofluorescence staining of Human ENPP7 in HT29 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with ENPP7 Monoclonal Antibody (10) (Product # MA5-29243, 1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cell membrane.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-29243
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
10
Immunogen
Recombinant Human ENPP7 protein (Met1-Ser439)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human ENPP7.
Target Information
ENPP7 converts sphingomyelin to ceramide. ENPP7 also has phospholipase C activity toward palmitoyl lyso-phosphocholine. ENPP7 does not appear to have nucleotide pyrophosphatase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alkaline sphingomyelin phosphodiesterase; alkaline sphingomyelinase; intestinal alkaline sphingomyelinase; unnamed protein product
Gene Aliases: ALK-SMase; E-NPP 7; NPP-7; NPP7
UniProt ID: (Human) Q6UWV6
Entrez Gene ID: (Human) 339221
sphingomyelin metabolic process
negative regulation of DNA replication
negative regulation of cell proliferation
lipid digestion
positive regulation of intestinal cholesterol absorption
glycosphingolipid catabolic process
fatty acid homeostasis
regulation of intestinal lipid absorption
positive regulation of ceramide biosynthetic process
positive regulation of sphingomyelin catabolic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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