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Invitrogen
ARF6 Recombinant Rabbit Monoclonal Antibody (JF101-2)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-32558
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JF101-2
Immunogen
Synthetic peptide within Human ARF6 aa 133-165.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
ARF6 (ADP-ribosylation factor 6) is a broadly expressed, differentially regulated GTPase that is present in cytoplasm and on both cell-surface and intracellular membranes and whose functions may include tissue-specific effects on vesicular trafficking during cellular differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP ribosylation factor 6; ARF6; DKFZp564M0264; small GTP binding protein; unnamed protein product
UniProt ID: (Human) P62330, (Mouse) P62331, (Rat) P62332
Entrez Gene ID: (Human) 382, (Mouse) 11845, (Rat) 79121
intracellular protein transport
cell adhesion
regulation of neuron projection development
positive regulation of neuron projection development
vesicle-mediated transport
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
endocytic recycling
protein localization to cell surface
regulation of Rac protein signal transduction
protein localization to endosome
negative regulation of receptor-mediated endocytosis
synaptic vesicle endocytosis
positive regulation of protein secretion
regulation of filopodium assembly
positive regulation of keratinocyte migration
regulation of dendritic spine development
protein localization to plasma membrane
ruffle assembly
maintenance of postsynaptic density structure
positive regulation of focal adhesion disassembly
positive regulation of protein localization to plasma membrane
positive regulation of mitotic cytokinetic process
protein localization to cleavage furrow
regulation of presynapse assembly
cellular response to nerve growth factor stimulus
negative regulation of protein localization to cell surface
negative regulation of dendrite development
liver development
protein transport
myeloid cell apoptotic process
regulation of toll-like receptor 4 signaling pathway
establishment of epithelial cell polarity
hepatocyte apoptotic process
actin cytoskeleton organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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