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Invitrogen

Phospho-CDK1/CDK2 (Thr14) Recombinant Rabbit Monoclonal Antibody (6R1O7)

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Phospho-CDK1/CDK2 (Thr14) Recombinant Rabbit Monoclonal Antibody (6R1O7)

Product Details

MA5-35854

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6R1O7

Immunogen

A synthetic phosphorylated peptide around T14 of human Cdk1/2CDK1 (P06493)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.04 mg/mL

Amount

104 µg

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849752

Product Specific Information

Immunogen sequence: EGTYG

Target Information

Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: cdc2-related protein kinase; CDK1; CDK2; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; Cell division control protein 2 homolog; cell division cycle 2 homolog A; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; Cell division protein kinase 1; Cell division protein kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 1; Cyclin-dependent kinase 2; p33 protein kinase; p34 protein kinase; unnamed protein product

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Gene Aliases: A630093N05Rik; CDC2; CDC28A; Cdc2a; CDK1; CDK2; CDKN1; CDKN2; p33(CDK2); p34; P34CDC2

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UniProt ID: (Human) P06493, (Human) P24941, (Rat) P39951, (Mouse) P11440, (Mouse) P97377

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Entrez Gene ID: (Human) 983, (Human) 1017, (Rat) 54237, (Mouse) 12534, (Rat) 362817, (Mouse) 12566

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Function(s)
nucleotide binding virus receptor activity chromatin binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity kinase activity transferase activity cyclin binding Hsp70 protein binding histone kinase activity cyclin-dependent protein kinase activity protein serine kinase activity magnesium ion binding protein domain specific binding metal ion binding transferase activity, transferring phosphorus-containing groups protein complex binding non-receptor serine/threonine protein kinase
Process(es)
G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle microtubule cytoskeleton organization DNA replication DNA repair chromatin remodeling regulation of transcription from RNA polymerase II promoter apoptotic process cellular response to DNA damage stimulus nuclear envelope organization mitotic nuclear envelope disassembly mitotic G2 DNA damage checkpoint centrosome cycle pronuclear fusion response to toxic substance positive regulation of gene expression negative regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle regulation of Schwann cell differentiation response to amine response to activity cell migration protein deubiquitination peptidyl-threonine phosphorylation chromosome condensation epithelial cell differentiation protein localization to kinetochore positive regulation of protein import into nucleus response to hydrogen peroxide regulation of circadian rhythm negative regulation of apoptotic process mitotic cell cycle phase transition response to ethanol positive regulation of DNA replication regulation of embryonic development thymidine biosynthetic process response to cadmium ion response to copper ion viral entry into host cell microtubule polymerization fibroblast proliferation rhythmic process response to axon injury cell division ventricular cardiac muscle cell development positive regulation of cardiac muscle cell proliferation cilium disassembly positive regulation of mitotic sister chromatid segregation protein-containing complex assembly cellular response to hydrogen peroxide ERK1 and ERK2 cascade Golgi disassembly DNA strand resection involved in replication fork processing positive regulation of protein localization to nucleus regulation of mitotic attachment of spindle microtubules to kinetochore microtubule cytoskeleton organization involved in mitosis DNA synthesis involved in mitotic DNA replication positive regulation of mitochondrial ATP synthesis coupled electron transport protein localization to site of double-strand break mitotic DNA-dependent DNA replication negative regulation of transcription from RNA polymerase II promoter telomere maintenance transcription, DNA-templated protein phosphorylation potassium ion transport centriole replication signal transduction Ras protein signal transduction regulation of mitotic cell cycle positive regulation of cell proliferation regulation of G2/M transition of mitotic cell cycle regulation of gene expression peptidyl-serine phosphorylation positive regulation of heterochromatin assembly mitotic G1 DNA damage checkpoint protection from non-homologous end joining at telomere positive regulation of DNA-dependent DNA replication initiation telomere maintenance in response to DNA damage post-translational protein modification positive regulation of transcription, DNA-templated centrosome duplication meiotic cell cycle cellular response to nitric oxide cellular senescence regulation of anaphase-promoting complex-dependent catabolic process mitotic cell cycle protein complex assembly mitotic nuclear division cell aging response to organonitrogen compound response to organic cyclic compound histone phosphorylation organ regeneration positive regulation of protein import into nucleus, translocation response to drug positive regulation of mitotic cell cycle cell cycle phosphorylation lens development in camera-type eye response to estradiol cellular response to insulin stimulus response to cAMP response to electrical stimulus regulation of cell cycle regulation of gene silencing
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