Invitrogen

RAB3a Monoclonal Antibody (1531CT562.14.57)

Name: RAB3a Monoclonal Antibody (1531CT562.14.57)
Brand: Invitrogen
SKU: MA5-37684
Price: 518.00 USD
Availability: InStock

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Antibody Testing Data (8)
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RAB3a Antibody in Immunocytochemistry (ICC/IF)

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RAB3a Antibody (MA5-37684) in ICC/IF

Immunocytochemistry/Immunofluorescent analysis of RAB3a in 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized PC-12 cells using RAB3a Monoclonal Antibody (Product # MA5-37684) at a 1:25 dilution, followed by Dylight® 488-conjugated goat anti-mouse IgG secondary antibody at 1:200 dilution (green). Immunofluorescence image showing cytoplasm staining on PC-12 cell line. Cytoplasmic actin is detected with Dylight® 554 Phalloidin at 1:100 dilution (red).The nuclear counter stain is DAPI (blue).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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RAB3a Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across multiple tissues owing to their inherent genetic constitution. Relative expression of RAB3A was observed in Rat brain and cerebellum but not in Rat skeletal muscle and liver using RAB3A Monoclonal Antibody (1531CT562.14.57) (Product # MA5-37684) in Western Blot. {RE}

Product Details

MA5-37684

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

Immunocytochemistry (ICC/IF)

1:25

Flow Cytometry (Flow)

1:25

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1531CT562.14.57

Immunogen

RAB3a recombinant protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

100 µg

Purification

Protein G

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2897608

Target Information

Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related small GTP binding protein 3A; unnamed protein product

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Gene Aliases: RAB3; SCA52

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UniProt ID: (Human) P20336, (Rat) P63012, (Mouse) P63011

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Entrez Gene ID: (Human) 5864, (Rat) 25531, (Mouse) 19339

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Function(s)

GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding protein binding, bridging GTP-dependent protein binding myosin V binding ATPase activator activity GDP-dissociation inhibitor binding ATPase binding

Process(es)

plasma membrane repair respiratory system process exocytosis mitochondrion organization neuromuscular synaptic transmission axonogenesis post-embryonic development regulation of synaptic vesicle priming regulation of dopamine secretion synaptic vesicle exocytosis synaptic vesicle maturation calcium ion regulated exocytosis regulation of exocytosis insulin secretion lung development regulation of synaptic vesicle fusion to presynaptic membrane lysosome localization Rab protein signal transduction synaptic vesicle recycling regulated exocytosis regulation of short-term neuronal synaptic plasticity synaptic vesicle transport maintenance of presynaptic active zone structure sensory perception of touch response to electrical stimulus acrosomal vesicle exocytosis evoked neurotransmitter secretion synaptic vesicle clustering regulation of presynaptic dense core granule exocytosis positive regulation of regulated secretory pathway regulation of plasma membrane repair regulation of synaptic vesicle exocytosis constitutive secretory pathway positive regulation of exocytosis regulation of long-term synaptic potentiation

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RAB3a Monoclonal Antibody (1531CT562.14.57)

RAB3a Antibody (MA5-37684) in ICC/IF

Product Details

MA5-37684

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Amount

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

References (0)

Bioinformatics

Performance Guarantee

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