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Invitrogen
SUFU Monoclonal Antibody (1783CT536.263.29)
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FIGURE: 1 / 2
SUFU Antibody (MA5-37736) in IHC (P)
Immunohistochemistry (Paraffin) analysis of SUFU in mouse embryo tissue sections using the SUFU Monoclonal Antibody (Product # MA5-37736) at a dilution of 1:25. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1:25) for 1 hours at 37°C. A undiluted b... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-37736
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1783CT536.263.29
Immunogen
recombinant protein of human SUFU
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: negative regulator of hedgehog signaling; novel; novel PEST-containing protein; novel; su(fu); OTTHUMP00000020377; OTTHUMP00000020378; OTTHUMP00000020379; RP11-47A8.1; unnamed protein product
Gene Aliases: BCNS2; JBTS32; PRO1280; Su(fu); SUFUH; SUFUXL
UniProt ID: (Human) Q9UMX1, (Mouse) Q9Z0P7
Entrez Gene ID: (Human) 51684, (Mouse) 24069
negative regulation of transcription from RNA polymerase II promoter
neural tube closure
heart looping
ventricular septum development
regulation of transcription, DNA-templated
signal transduction
smoothened signaling pathway
spermatid development
determination of left/right symmetry
positive regulation of protein processing
spinal cord dorsal/ventral patterning
aorta development
skin development
negative regulation of smoothened signaling pathway
coronary vasculature development
maintenance of protein localization in organelle
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of cellular response to drug
negative regulation of protein import into nucleus
negative regulation of osteoblast differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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