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Invitrogen
CEACAM6 Monoclonal Antibody (A1E2)
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FIGURE: 1 / 8
CEACAM6 Antibody (MA5-37801) in ICC/IF
Immunocytochemical analysis of CD66c (CEACAM6) in MCF-7 cells using a CD66c (CEACAM6) monoclonal antibody (Product #MA5-37801). Formalin fixed cells, as seen in green, were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with the primary antibody ( 1:100) for 1 hour at room temperature, washed with PBS. Alexa Fluor®488 Goat anti-Mouse IgG was used as the secondary antibody at 1:1,000 dilution. The nuclear counter stain is DA... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-37801
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
A1E2
Immunogen
Recombinant protein within Human CEACAM6 aa 1-160.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive controls: JAR cell lysate, SK-Br-3 cell lysate, A549, HT-29, MCF-7, human lung tissue, human colon tissue, human colon carcinoma tissue, SW620.
Target Information
CEA Cell Adhesion Molecule 6 (CEACAM6) belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. CEACAM6 affects the sensitivity of tumor cells to adenovirus infection. The acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BGP; BGP-1; carcinoembryonic antigen related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66d; CD66e; CEA; CEACAM-1; CEACAM-3; CEACAM-5; CEACAM-6; CGM1; Cluster of Differentiation 66c; nonspecific crossreacting antigen precursor; normal cross-reacting antigen; ORF1; ORF2; pan CEACAM; unnamed protein product
Gene Aliases: CD66c; CEAL; NCA; NCA-50/90
UniProt ID: (Human) P40199
Entrez Gene ID: (Human) 4680
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
positive regulation of cell proliferation
positive regulation of cell migration
positive regulation of heterotypic cell-cell adhesion
positive regulation of endothelial cell-matrix adhesion via fibronectin
negative regulation of anoikis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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