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Invitrogen
TC10 Recombinant Rabbit Monoclonal Antibody (10F7Y7)
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FIGURE: 1 / 3
TC10 Antibody (MA5-37999) in IHC (P)
Immunohistochemistry analysis of TC10 in paraffin-embedded rat spleen. Samples were incubated with TC10 Monoclonal antibody (Product # MA5-37999) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-37999
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
10F7Y7
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 100-205 of human TC10/RHOQ (P17081)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.19 mg/mL
Amount
119 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: 293T, A-549, 22Rv1, Mouse heart, Rat heart
Immunogen sequence: KEEWVPELKE YAPNVPFLLI GTQIDLRDDP KTLARLNDMK EKPICVEQGQ KLAKEIGACC YVECSALTQK GLKTVFDEAI IAILTPKKHT VKKRIGSRCI NCCLIT
Target Information
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 42; ras homolog gene family, member Q; ras-like protein; ras-like protein family member 7A; ras-like protein TC10; RAS-like, family 7, member A; ras-related GTP-binding protein TC10; small GTPase Tc10
Gene Aliases: ARHQ; HEL-S-42; RASL7A; TC10; TC10A
UniProt ID: (Human) P17081, (Mouse) Q8R527, (Rat) Q9JJL4
Entrez Gene ID: (Human) 23433, (Mouse) 104215, (Rat) 85428
endocytosis
actin filament organization
signal transduction
small GTPase mediated signal transduction
insulin receptor signaling pathway
establishment of cell polarity
actin cytoskeleton organization
cortical actin cytoskeleton organization
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
GTP metabolic process
positive regulation of glucose import
positive regulation of filopodium assembly
negative regulation of protein localization to plasma membrane
regulation of cell shape
negative regulation of glucose import
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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