Search

  • Order Status
  • Quick Order
  • Promos

Invitrogen

TACR1 Recombinant Rabbit Monoclonal Antibody (1E5)

View all (26) TACR1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Datasheet
Certificates
Protocols
Questions & Answers
Datasheet
Certificates
Protocols
Questions & Answers
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
TACR1 Recombinant Rabbit Monoclonal Antibody (1E5)

Product Details

MA5-38359

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:5,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

1E5

Immunogen

A synthesized peptide derived from human Neurokinin 1 Receptor (aa 367-381).
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Amount

110 µg

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol, 150mM NaCl

Contains

0.02% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898273

Product Specific Information

This antibody has been tested in direct-ELISA

Target Information

Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: G-protein coupled receptor; substance P receptor; neurokinin receptor 1; NK-1 receptor; NK-1R; Nk1 receptor; substance P receptor; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); unnamed protein product

View more View less

Gene Aliases: NK1R; NKIR; SPR; TAC1R

View more View less

UniProt ID: (Human) P25103, (Mouse) P30548

View more View less

Entrez Gene ID: (Human) 6869, (Mouse) 21336

View more View less

Function(s)
G-protein coupled receptor activity tachykinin receptor activity protein binding substance P receptor activity
Process(es)
aggressive behavior positive regulation of leukocyte migration angiotensin-mediated drinking behavior inflammatory response G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration phospholipase C-activating tachykinin receptor signaling pathway tachykinin receptor signaling pathway learning or memory long-term memory regulation of blood pressure associative learning detection of abiotic stimulus response to hormone response to ozone positive regulation of epithelial cell migration response to auditory stimulus regulation of smooth muscle cell migration positive regulation of synaptic transmission, cholinergic positive regulation of synaptic transmission, GABAergic response to estradiol response to progesterone response to nicotine operant conditioning sperm ejaculation eating behavior positive regulation of vascular permeability response to ethanol positive regulation of action potential positive regulation of blood pressure positive regulation of ossification positive regulation of vasoconstriction positive regulation of hormone secretion behavioral response to pain regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation positive regulation of epithelial cell proliferation positive regulation of stress fiber assembly response to electrical stimulus smooth muscle contraction involved in micturition regulation of uterine smooth muscle contraction positive regulation of uterine smooth muscle contraction positive regulation of sperm motility response to pain
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support