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Alpha-hemolysin (Atidortoxumab Biosimilar) Recombinant Human Monoclonal Antibody
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FIGURE: 1 / 1
Alpha-hemolysin (Atidortoxumab Biosimilar) Antibody (MA5-42168) in SDS-PAGE
SDS-PAGE analysis of the recombinant Staphylococcus aureus alpha toxin, bi-component leukocidins protein expressed in CHO cells using a Alpha-hemolysin (Atidortoxumab Biosimilar) monoclonal antibody (Product # MA5-42168). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-42168
Product Specifications
Species Reactivity
Bacteria
Host/Isotype
Human
/ IgG1, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Staphylococcus aureus alpha toxin, bi-component leukocidins
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Target Information
Alpha-hemolysin, also known as Hla, is a protein encoded by the hla gene in Staphylococcus aureus, a common pathogenic bacterium. The hla gene is located on the chromosome of Staphylococcus aureus. Alpha-hemolysin is a beta-barrel pore-forming toxin that disrupts the plasma membranes of host cells by creating transmembrane pores, leading to cell lysis and death. It plays a critical role in S. aureus pathogenicity by destroying red blood cells (hemolysis), white blood cells, and epithelial cells, facilitating tissue infection and immune evasion. The structure of alpha-hemolysin consists of a heptameric pore formed by seven identical monomers, each contributing a beta-strand to the formation of the pore.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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