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Invitrogen
MAdCAM-1 (Ontamalimab Biosimilar) Recombinant Human Monoclonal Antibody
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FIGURE: 1 / 2
MAdCAM-1 (Ontamalimab Biosimilar) Antibody (MA5-42181) in ELISA
ELISA binding of MAdCAM-1 (Ontamalimab Biosimilar) to immobilized recombinant antigen (coated at 5 µg/mL). MAdCAM-1 (Ontamalimab Biosimilar) monoclonal (Product # MA5-42181) antibody was serially diluted from 10,000 ng/mL to 0.64 ng/mL.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-42181
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG2, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Human MADCAM1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.63 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.5
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Target Information
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hMAdCAM-1; MAdCAM-1; MADCAM1
Gene Aliases: MACAM1
UniProt ID: (Human) Q13477
Entrez Gene ID: (Human) 8174
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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