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Invitrogen
Ganglioside GD2 (Naxitamab Biosimilar) Recombinant Human Monoclonal Antibody
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FIGURE: 1 / 1
Ganglioside GD2 (Naxitamab Biosimilar) Antibody (MA5-42231) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human Ganglioside GD2 protein expressed in CHO cells using a B4GALNT1 (Naxitamab Biosimilar) monoclonal antibody (Product # MA5-42231). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-42231
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Human Ganglioside GD2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
3.45 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
This product is a Humanized mouse antibody.
Target Information
Ganglioside GD2 is a disialoganglioside (glycosphingolipid) expressed on the outer surface of the plasma membrane. It is highly expressed in tumors of neuroectodermal origin, including neuroblastoma, melanoma, osteosarcoma, and small cell lung cancer, while showing limited distribution in normal tissues, primarily in peripheral nerves and the central nervous system. GD2 plays roles in cell adhesion, migration, and signal transduction. Because of its high tumor expression and restricted normal tissue distribution, GD2 is an established target for antibody-based immunotherapies, particularly in high-risk neuroblastoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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