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Invitrogen
Versican Recombinant Rabbit Monoclonal Antibody (6D8K9)
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FIGURE: 1 / 4
Versican Antibody (MA5-42721) in ICC/IF
Immunofluorescence analysis of Versican was performed using 70% confluent log phase SK-O-V3 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Versican Recombinant Rabbit Monoclonal Antibody (6D8K9) (Product # MA5-42721, 1:100) in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy chain), Superclonal™ Recombinant Secondary Antibody, A... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-42721
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6D8K9
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Amount
40 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QGAHLTSILS HEEQMFVNRV GHDYQWIGLN DKMFEHDFRW TDGSTLQYEN WRPNQPDSFF SAGEDCVVII WHENGQWNDV PCNYHLTYTC KKGTVACGQP PVVENAKTFG KMKPRYEINS LIRYHCKDGF IQRHLPTIRC LGNGRWAIPK ITCMNPSAYQ RTYSMKYFKN SSSAKDNSIN TSKHDHRWSR RWQESRR
Target Information
Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican's existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chondroitin sulfate proteoglycan core protein; chondroitin sulfate proteoglycan core protein 2; glial hyaluronate-binding protein; hyaluronan-binding chondroitin sulfate proteoglycan; large fibroblast proteoglycan; PG-M core protein; PGM; unnamed protein product; V1 Neo; versican proteoglycan; Versican V0; WGN 1
Gene Aliases: 5430420N07Rik; 9430051N09; CSPG2; DPEAAE; ERVR; GHAP; hdf; PG-M; PG-M(V0); PG-M(V1); WGN; WGN1
UniProt ID: (Human) P13611
Entrez Gene ID: (Human) 1462, (Mouse) 13003
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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