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Invitrogen
Beta III Tubulin Recombinant Rabbit Monoclonal Antibody (HL1708)
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FIGURE: 1 / 2
Beta III Tubulin Antibody (MA5-47147) in ICC/IF
Immunofluorescent analysis of Beta III Tubulin in DIV9 rat E18 primary hippocampal neuron cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: beta Tubulin 3/ Tuj1 stained by beta Tubulin 3/ Tuj1 monoclonal antibody (Product # MA5-47147) diluted at 1:250. Blue: Fluoroshield with DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-47147
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1708
Immunogen
Synthetic peptide of human beta Tubulin 3/ Tuj1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta 3 tubulin; beta tubulin 3; betaIII-tubulin; class III beta-tubulin; MC1R; microtubule protein; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; tubulin beta; Tubulin beta-3; Tubulin beta-4; tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3; unnamed protein product
Gene Aliases: 3200002H15Rik; beta-4; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; M(beta)3; M(beta)6; TUBB4
UniProt ID: (Human) Q13509, (Rat) Q4QRB4, (Mouse) Q9ERD7
Entrez Gene ID: (Human) 10381, (Rat) 246118, (Mouse) 22152
GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding
netrin receptor binding
double-stranded RNA binding
calcium ion binding
protein domain specific binding
ubiquitin protein ligase binding
GTPase activating protein binding
MHC class I protein binding
macromolecular complex binding
microtubule cytoskeleton organization
mitotic cell cycle
microtubule-based process
axon guidance
biological_process
neuron differentiation
sperm motility
negative regulation of microtubule polymerization
netrin-activated signaling pathway
regulation of synapse organization
spindle assembly
odontoblast differentiation
dorsal root ganglion development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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