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Invitrogen

ApoA1 Recombinant Rabbit Monoclonal Antibody (HL1713)

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ApoA1 Recombinant Rabbit Monoclonal Antibody (HL1713)

Product Details

MA5-47151

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:10,000
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

HL1713

Immunogen

Full length human Apolipoprotein A1 recombinant protein.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2938223

Product Specific Information

Store as concentrated solution.

Centrifuge briefly prior to opening vial.

Target Information

Apolipoprotein A-1 (apo A-1) in human plasma is a major protein component of high density lipoprotein (HDL). The molecular mass is 24 kDa. Apo A-1 is a cofactor for enzymes involved in the normal turnover of cholesterol and is produced in the liver. Plasma concentration is 270-380 mg/100 mL.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 1-Sep; 2-Sep; Apo a; apo A-1; APO A1; APO I; apo-AI; APOA-I; ApoAI; Apolipoprotein; apolipoprotein A-1; apolipoprotein A1; apolipoprotein A1 homolog; Apolipoprotein AI; epididymis secretory sperm binding protein; MGC102525; MGC117399; MGC124929; preproapolipoprotein A-I; proapo-A-I protein; proapolipoprotein; Udpgt; Ugt1; Ugt1a7; unnamed protein product

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Gene Aliases: Alp-1; AMYLD3; apo(a); apo-AI; Apoa-1; apoA-I; Brp-14; HPALP2; Ltw-1; Lvtw-1; Sep-1; Sep-2; Sep2

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UniProt ID: (Human) P02647, (Rat) P04639, (Mouse) Q00623

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Entrez Gene ID: (Human) 335, (Rat) 25081, (Mouse) 11806

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Function(s)
beta-amyloid binding receptor binding lipid transporter activity protein binding phospholipid binding high-density lipoprotein particle binding lipid binding cholesterol binding enzyme binding heat shock protein binding apolipoprotein receptor binding apolipoprotein A-I receptor binding identical protein binding protein homodimerization activity chemorepellent activity receptor agonist activity phosphatidylcholine-sterol O-acyltransferase activator activity high-density lipoprotein particle receptor binding lipoprotein particle binding intermembrane cholesterol transfer activity lipase inhibitor activity
Process(es)
regulation of protein phosphorylation endothelial cell proliferation negative regulation of cytokine production involved in immune response phospholipid metabolic process phosphatidylcholine biosynthetic process cholesterol biosynthetic process lipid transport transforming growth factor beta receptor signaling pathway G-protein coupled receptor signaling pathway integrin-mediated signaling pathway response to nutrient cholesterol metabolic process glucocorticoid metabolic process response to xenobiotic stimulus negative regulation of tumor necrosis factor-mediated signaling pathway positive regulation of cholesterol efflux negative regulation of very-low-density lipoprotein particle remodeling peripheral nervous system axon regeneration phospholipid transport protein oxidation peptidyl-methionine modification lipid storage regulation of intestinal cholesterol absorption cholesterol transport adrenal gland development organ regeneration regulation of Cdc42 protein signal transduction negative regulation of interleukin-1 beta production cholesterol efflux phospholipid efflux negative regulation of heterotypic cell-cell adhesion beta-amyloid formation high-density lipoprotein particle remodeling high-density lipoprotein particle assembly positive regulation of Rho protein signal transduction lipoprotein metabolic process lipoprotein biosynthetic process cholesterol homeostasis blood vessel endothelial cell migration response to estrogen reverse cholesterol transport negative regulation of inflammatory response positive regulation of phagocytosis protein stabilization negative chemotaxis vitamin transport negative regulation of hydrolase activity positive regulation of stress fiber assembly acylglycerol homeostasis phospholipid homeostasis negative regulation of lipase activity negative regulation of cell adhesion molecule production negative regulation of response to cytokine stimulus triglyceride homeostasis ERK1 and ERK2 cascade cholesterol import cellular response to lipoprotein particle stimulus positive regulation of cholesterol metabolic process positive regulation of substrate adhesion-dependent cell spreading positive regulation of phospholipid efflux high-density lipoprotein particle clearance cellular response to beta-amyloid
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