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Invitrogen
ASCT2 Recombinant Rabbit Monoclonal Antibody (HL1988)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-47250
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Cat,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1988
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human SLC1A5. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
SLC1A5 (Solute carrier family 1 (neutral amino acid transporter), member 5) is a member of the Na(+)-dependent amino acid transporter superfamily. It has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. It acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alanine/serine/cysteine transporter 2; ASC amino acid transporter-2; ASC-like Na(+)-dependent neutral amino acid transporter ASCT2; ASCT2; ATB(0); ATB0; baboon M7 virus receptor; cell-surface receptor; insulin-activated amino acid transporter; neutral amino acid transporter; neutral amino acid transporter B; RD114 virus receptor; RD114/simian type D retrovirus receptor; receptor for baboon endogenous retrovirus; sodium-dependent neutral amino acid transporter type 2; solute carrier family 1 (neutral amino acid transporter), member 5; solute carrier family 1 member 5; solute carrier family 1, member 7; unnamed protein product
Gene Aliases: AAAT; ASCT2; ATBO; M7V1; M7VS1; R16; RDRC; Slc1a7
UniProt ID: (Human) Q15758
Entrez Gene ID: (Human) 6510, (Mouse) 20514
protein binding
amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-aspartate transmembrane transporter activity
L-glutamine transmembrane transporter activity
L-serine transmembrane transporter activity
symporter activity
antiporter activity
ligand-gated channel activity
signaling receptor activity
amino acid transport
glutamine transport
glutamine secretion
neutral amino acid transport
L-serine transport
erythrocyte differentiation
protein homotrimerization
glutamate homeostasis
L-aspartate import across plasma membrane
transport across blood-brain barrier
L-glutamine import across plasma membrane
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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