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Invitrogen
Annexin A1 Recombinant Mouse Monoclonal Antibody (3E8)
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FIGURE: 1 / 2
Annexin A1 Antibody (MA5-50253) in IHC (P)
Immunohistochemistry analysis with a Annexin A1 monoclonal antibody (Product # MA5-50253) using a dilution of 1:30 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was in... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-50253
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
3E8
Immunogen
Recombinant Human ANXA1 protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.933 mg/mL
Amount
93.3 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANAX1; annexin I; annexin I (lipocortin I); annexin-1; ANX1; ANXA1; calpactin II; calpactin-2; chromobindin-9; epididymis secretory sperm binding protein; lipocortin I; LPC1; phospholipase A2 inhibitory protein; RP11-71A24.1; unnamed protein product
Gene Aliases: ANX1; LPC1
UniProt ID: (Human) P04083
Entrez Gene ID: (Human) 301
phosphatidylserine binding
phospholipase inhibitor activity
receptor binding
calcium ion binding
protein binding
phospholipid binding
calcium-dependent phospholipid binding
lipid binding
phospholipase A2 inhibitor activity
calcium-dependent protein binding
cadherin binding involved in cell-cell adhesion
neutrophil homeostasis
monocyte chemotaxis
regulation of leukocyte migration
phagocytosis
inflammatory response
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
regulation of cell shape
myoblast migration involved in skeletal muscle regeneration
peptide cross-linking
actin cytoskeleton organization
keratinocyte differentiation
positive regulation of vesicle fusion
regulation of interleukin-1 production
negative regulation of interleukin-8 production
positive regulation of interleukin-2 production
positive regulation of neutrophil apoptotic process
cellular response to vascular endothelial growth factor stimulus
positive regulation of T cell proliferation
neutrophil activation
negative regulation of apoptotic process
positive regulation of T-helper 1 cell differentiation
negative regulation of T-helper 2 cell differentiation
negative regulation of exocytosis
alpha-beta T cell differentiation
regulation of hormone secretion
regulation of inflammatory response
negative regulation of transport
positive regulation of multicellular organismal process
cellular response to glucocorticoid stimulus
granulocyte chemotaxis
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of wound healing
neutrophil clearance
cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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